Model Animal Mimicking Human Virus-induced Diabetes
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چکیده
منابع مشابه
Animal models mimicking aminoglycoside-induced renal damage
Aminoglycoside antibiotics consisting gentamicin, kanamycin, amikacin and other can cause acute kidney injury (1). This is a common problem in intensive care medicine (2). It could be fatal (3) or can progress towards chronic kidney disease in survivors (4). Knowledge of the possible mechanisms involved in aminoglycoside-induced nephrotoxicity is largely due to the use of experimental animals (...
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Several medicinal plants are having hypoglycemic effects.[1], The World Health Organization has recommended that the assessment of traditional plant treatments for diabetes mellitus needs further investigation.[2], Several herbal medicines were described for the care of diabetes mellitus in ancient literature of Ayurveda in India. Many of the plants used as diet were reported to have antidiabet...
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BACKGROUND Flavonoid-rich aqueous fraction of methanolic extract of Hibiscus sabdariffa calyx was evaluated for its anti-hepatotoxic activities in streptozotocin-induced diabetic Wistar rats. METHODS Diabetes Mellitus was induced in Wistar rats by a single i.p injection of 80 mg/kg b.w. streptozotocin (STZ) dissolved in 0.1 M citrate buffer (pH 6.3). RESULTS The ameliorative effects of the ...
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PURPOSE Nonsteroidal anti-inflammatory drugs (NSAIDs) are used for the treatment of many joint disorders, inflammation and to control pain. Numerous reports have indicated that NSAIDs are capable of producing nephrotoxicity in human. Therefore, the objective of this study was to evaluate mefenamic acid, a NSAID nephrotoxicity in an animal model. METHODS Mice were dosed intraperitoneally with ...
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Carpel tunnel syndrome (CTS) is a condition in which median nerve compression results in paresthesias and pain in thewrist and hand. We are going to report a rare case of topiramate-induced neuropathy which clinically resembles CTS.Discontinuation of topiramate resulted in spontaneous resolution of numbness, paresthesia and pain in a few days. Highclinical suspicion is advised in patients who a...
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ژورنال
عنوان ژورنال: EBioMedicine
سال: 2018
ISSN: 2352-3964
DOI: 10.1016/j.ebiom.2018.05.018